Bayer Leverkusen vs 1. FC Nürnberg Prediction

Bayer Leverkusen host 1. FC Nürnberg on 28 October 2026 at 22:45 in the DFB Pokal. Leverkusen arrive as heavy favorites despite a 3-0 loss to Hoffenheim last weekend that ended their six-match winning run across all competitions. Manager Carles Martínez blamed fixture congestion—the squad returned late from a Europa League win in Greece—and will rotate his lineup to manage fatigue. Nürnberg, from the second tier, lost 1-0 to Kaiserslautern midweek and have taken just one point from their last three league matches. Both teams arrive weakened: Leverkusen will be without Diaby (hamstring) and Báde (concussion), while Nürnberg miss key defender Otto and forward Zoma (both injured).

Form and H2H

Leverkusen have won seven of their last ten home matches, averaging 2.4 goals for and 1.2 against. Nürnberg's away record shows five wins in ten, with 2.2 goals for and 1.4 conceded per game. The head-to-head record heavily favors Leverkusen: they have won four of the last six meetings, including a 3-0 home victory in November 2013. Nürnberg's sole standout result came in December 2011 with a 3-0 away win, but Leverkusen have dominated since. Nürnberg rank second in second-tier scoring with 21 goals in nine matches, led by forwards Schöberl and Zoma (12 combined), though Zoma's absence removes a key attacking threat.

Best bet

Bayer Leverkusen to win with a -2.5 handicap. Leverkusen's class advantage, home record, and attacking depth make them clear favorites even with rotation. At home this season they have won all four official matches 10-1. Nürnberg will be undermanned and face a side capable of creating multiple chances. At Melbet this bet trades at 1.13, at 1xBet at 1.14, and at 1Win at 1.15.

Odds to watch

Leverkusen's attacking potential and Nürnberg's defensive vulnerabilities suggest a high-scoring match. Leverkusen recently beat Mainz 4-3 and Lech 4-0, while Nürnberg drew 4-4 with Wolfsburg. The cup format encourages open play if either team needs to chase the game. Over 2.5 goals is available at Mostbet at 7.4 for the draw and 12 for an away win, with the home win priced at 1.16.