1899 Hoffenheim vs Lyon Prediction

Hoffenheim host Lyon on 22 October 2026 at 22:00 in the third round of the Europa League league phase. Lyon arrive in far stronger form: two wins from two group matches leave them sixth on six points, while Hoffenheim sit bottom with zero points after losses to OFI and Beşiktaş. The German side conceded three goals in each of those defeats and have managed only two goals across their last nine competitive matches. Lyon's away record in Europe this season stands at six wins from nine outings, and they have not lost any of their last ten Europa League road games. Hoffenheim's home record tells a different story: three losses in four domestic league matches this season, though they did beat Borussia Mönchengladbach 2–1 in their most recent outing to snap a four-game losing streak.

Form and H2H

Hoffenheim have won three and drawn one of their last ten matches across all competitions, but conceded 2.1 goals per game over that span. Lyon won six of their last ten away matches and conceded just 1.0 goal per game on the road. The teams have met three times: all three fixtures ended level, including a 2–2 draw at the Rhein-Neckar-Arena on 7 November 2024. Lyon scored in nine of their last ten recent matches across all competitions and created at least four shots on target in nine of their last ten Europa League away games. Hoffenheim found the net in eight of their last ten matches but face a Lyon defence that has not allowed more than two goals in any of their previous ten matches.

Best Bet

Lyon draw or win (X2) at 3.37 with 1xBet. Lyon's consistency on the road, combined with Hoffenheim's defensive fragility at home and recent offensive struggles, makes the away side's unbeaten run in European away matches the key factor. A draw would also extend the head-to-head pattern of stalemates between these sides.

Odds to Watch

Hoffenheim win trades at 2.07 with 1xBet, reflecting their home advantage and the fact that they have scored in eight of their last ten matches. The draw sits at 3.98. Over 2.5 goals carries appeal given Lyon's attacking threat and Hoffenheim's tendency to concede, though the away side's defensive discipline and Hoffenheim's recent low-scoring output suggest caution on higher totals.